Factor VIII (Recombinate / rAHF, Baxter / rurioctocog alpha)

Turkish adaptation and psychometric validation of the Normative Male Alexithymia Scale-Brief Form (NMAS-BF) among male university students.

Özel İrem İ

Normative male alexithymia reflects masculinity-related difficulties in identifying and expressing emotions and is theoretically linked to restrictive emotionality within masculine socialization. Existing measures predominantly assess clinical levels of alexithymia and may fail to capture subclinical, culturally embedded patterns of emotional restriction associated with masculine socialization. This study aimed to adapt the Normative Male Alexithymia Scale-Brief Form (NMAS-BF) to Turkish language and culture and to evaluate its psychometric properties. A methodological study was conducted with Turkish male university students. Linguistic equivalence was examined in a bilingual sample (n = 46), followed by a pilot study (n = 30). Separate non-overlapping samples were used for exploratory factor analysis (n = 376) and confirmatory factor analysis (n = 376) to assess structural validity. Exploratory factor analysis was conducted using principal axis factoring. Internal consistency was evaluated using Cronbach's alpha, corrected item-total correlations, and alpha-if-item-deleted values. The Turkish version of the NMAS-BF demonstrated high internal consistency (α = 0.890), with corrected item-total correlations ranging from 0.617 to 0.770. Exploratory factor analysis using principal axis factoring supported a single-factor structure explaining approximately 58.09% of the common variance. Confirmatory factor analysis indicated good model fit for the one-factor model, χ2(9) = 20.66, χ2/df = 2.30, RMSEA = 0.059, CFI = 0.99, TLI/NNFI = 0.99, SRMR = 0.025, and GFI = 0.98. The findings provide initial evidence for the internal consistency and structural validity of the Turkish NMAS-BF among Turkish male university students. Beyond its psychometric properties, the scale provides a culturally adapted tool for examining masculinity-related emotional restriction within the context of Turkish masculine socialization. Future studies may use the Turkish NMAS-BF to investigate associations between emotional restriction, emotional awareness, emotional expression, and psychological functioning among more diverse samples of Turkish men.

Nodule Morphology: A General Prognostic Factor or Treatment Strategy-Related Heterogeneity in Treatment Response?

Ni Handan H

Considerations on TNF-α inhibition in ligature-induced periodontitis mice with the Alzheimer's disease risk factor APOE4.

Ardila Carlos M CM, Pineda-Vélez Eliana E, Díaz-Laclaustra Alejandro I AI

Latent Structure and Incremental Validity of the Semi-Structured Interview for Personality Functioning DSM-5 (STiP-5.1) in a Lithuanian Adolescent Sample.

Grigaitė Agnė A, Gaudiešiūtė Elena E, Hutsebaut Joost J, Barkauskienė Rasa R

As personality functioning has become central to contemporary conceptualizations of personality pathology, understanding its structure and optimal assessment has emerged as an important research priority, particularly in adolescence. This study examined the latent structure of the Semi-Structured Interview for Personality Functioning DSM-5 (STiP-5.1) and its incremental validity in predicting functional impairment beyond self-reported personality functioning. Participants were 178 adolescents aged 11-18 years, including a clinical sample (n = 104) and a community sample (n = 74). Confirmatory factor analyses (CFA) and bifactor modeling were used to evaluate the latent structure of the STiP-5.1. Hierarchical regression analyses examined whether clinician-rated personality functioning explained additional variance in functional impairment (WHODAS 2.0) beyond self-reported personality functioning assessed with the LoPF-Q 12-18 Short. The bifactor model demonstrated the best overall fit and supported the predominance of a strong general factor. Most reliable variance was attributable to this factor, whereas self- and interpersonal-specific factors contributed little unique variance. A four-factor CFA model also demonstrated excellent fit, supporting differentiation among identity, self-direction, empathy, and intimacy. Clinician-rated personality functioning explained additional variance in functional impairment beyond self-report measures. Self-functioning, particularly the element of self-direction, emerged as a unique predictor of functional impairment. Findings support a predominantly unidimensional conceptualization of personality functioning in adolescence while retaining clinically meaningful differentiation across LPFS domains and elements. The STiP-5.1 provides unique information beyond self-report assessment, supporting multimethod approaches to the assessment of personality functioning in adolescents.